Continuous glucose monitoring predicts glycemic status in postpartum women with a recent history of gestational diabetes
Year: 2025
Type: article
Abstract: Background Women with a history of gestational diabetes mellitus (GDM) face an elevated risk of developing diabetes, yet postpartum screening is often This study evaluated the diagnostic utility of a blinded continuous glucose monitoring (CGM) system (Dexcom G7) for assessing glycemic status.Methods Of 40 enrolled participants, 39 completed testing at 6–24 weeks postpartum. Assessments included hemoglobin A1c (HbA1c,), fructosamine, a 75-g oral glucose tolerance test (OGTT), and 8–9 days of CGM wear. CGM metrics analyzed were mean glucose and time in range (TIR; 3.9–7.8 mmol/L).Results Diabetes and prediabetes were identified in 1 and 9 participants by HbA1c, 3 and 10 by fructosamine, and 4 and 10 by OGTT. CGM metrics detected 4 cases of diabetes and 10 of prediabetes. Mean OGTT glucose correlated strongly with mean CGM glucose (r = 0.66, p < 0.001) and inversely with TIR (r = –0.57, p < 0.001). Paired OGTT and CGM values were highly correlated (r = 0.874; p < 0.001).Conclusion Postpartum dysglycemia is prevalent after GDM. HbA1c and fructosamine lacked sensitivity and specificity, while CGM performed comparably to OGTT in detecting abnormal glucose metabolism in this postpartum population.Clinical trial registration http://www.clinicaltrials.gov identifier is NCT06057805
Source: Expert Review of Medical Devices
Institution: Woman's Hospital
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funders: American Diabetes Association, Dexcom
OpenAlex ID: W7116757708