Work

A Concise Total Synthesis of (+)-Pedrolide

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide A concise total synthesis of (+)-pedrolide has been accomplished. Key steps include an intramolecular Diels–Alder reaction to rapidly construct the tetracyclic carbon skeleton from (R)- carvone and the late-stage application of two different MHAT reactions in advancing the highly functionalized carane moiety.

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.5c17555

Authors: Hao Shen, Yushang Zhou, John L. Wood

Institution: Baylor University

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500