Electrical Versus Optical Generation of Leader Signals for Downconversion Leader-Follower Optical Coherence Tomography
Year: 2025
Type: article
Abstract: The paper refers to advancements in the production of en-face optical coherence tomography (OCT) images from different depths in a sample in real time, using Downconversion Leader-Follower optical coherence tomography method. So far, for a sample placed in an interferometer (Follower), all previous Downconversion Leader-Follower reports employed an interferometer (Leader) to determine the depth where the OCT signal is selected from. In this paper, for the first time, the Leader interferometer is replaced by an arbitrary waveform generator, i.e. optical generation of the reference signal to perform downconversion is replaced by electrical synthesis. In this way, en face images from different depths are presented in real time, without recurring to a second interferometer. Avenues opened by electrical synthesis of signals otherwise provided by interferometers are discussed, with potential to be adopted in signal processing, manipulation and presentation of high resolution images in orthogonal orientations to serve better diagnosis.
Source: IEEE photonics journal
Institution: University of Kent
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,075
Funders: Ministerio de Ciencia, Innovación y Universidades, National Institute for Health and Care Research, King's College London, European Commission, Moorfields Eye Hospital NHS Foundation Trust, Directorate for Biological Sciences, Medical Research Council, Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council
Awards: NExt generation of Tuneable LASers for optical coherence tomography, Compact Forward-Viewing Endoscopic Optical Coherence Tomography, An optical detector for latent fungal infection in produce, G5243237905, G5514925110, 5-Dimensional High-Resolution non-invasive assessment of mammalian Embryos (5DHiResE), G8184411421, BBSRC Pathfinder IAA University of Kent, MRC IAA 2021 University of Kent
OpenAlex ID: W7116795909
