Work

Design, Synthesis, and Biological Evaluation of a Series of Novel LFA-1 Antagonists with Enhanced Potency and Ocular Safety for Dry Eye Disease

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02250

Authors: Manman Sun, Jie Zhang, Aohui Hu, Jiacheng Wang, Kaile Yao, Xuebo Yang, Wanxing Ni, Lingchen Tan, Yu Zhang, Linxiang Zhao, Min Huang

Institutions: Shenyang Pharmaceutical University, Northeastern University, National University of Singapore

Language: English

Topic: Ocular Surface and Contact Lens

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, China Scholarship Council, Natural Science Foundation of Liaoning Province, Scientific Research Fund of Liaoning Provincial Education Department, Shenyang Pharmaceutical University

Awards: G1487114894, G2999114048, G3367054370, G7093086528, G8019466237, G8495666367, G8558620441, G92422190

OpenAlex ID: W7116837185

FWCI: 0.826

Cites: 31

Cited by: 1

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