Work

Metabolic-switch macrophage cyborgs reverse atherosclerosis by photoacoustic-directed on-demand phenotype delivery

Year: 2025

Type: article

Abstract: Engineered macrophage cyborgs home to atherosclerotic plaques for ultrasound/photoacoustic tracking and ultrasound-triggered immunomodulation, promoting M2 polarization and Treg recruitment to suppress inflammation and regress plaques.

Source: Materials Horizons

DOI: 10.1039/d5mh01682g

Authors: Wei Zeng, Weimin Fang, Yuhang Mao, Yalan Huang, Yan Lin, Leilei Wu, Anqi Chen, Zhengan Huang, Yuanyuan Sheng, Xiaoxuan Lin, Jiayu Ye, Yanbin Guo, Guanxi Wen, Jian Zeng, Jinfeng Xu, Liqiang Zhou, Yingying Liu

Institutions: Jinan University, Southern University of Science and Technology, ShenZhen People’s Hospital, Ankang University, Renmin Hospital of Wuhan University, Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital, Southern Medical University, University of Macau

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Natural Science Foundation of China, Fundo para o Desenvolvimento das Ciências e da Tecnologia, Science, Technology and Innovation Commission of Shenzhen Municipality, Shenzhen Science and Technology Innovation Program

Awards: G1046388526, G5505167818, G5738271314, G8155202315, G8477887797

OpenAlex ID: W7116861756

FWCI: 0.237

Cites: 57

Cited by: 1

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