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A case of type I gastric NET with AIG treated by ESD

Year: 2025

Type: article

Abstract: A 79-year-old man presented with abdominal pain. Esophagogastroduodenoscopy (EGD) revealed two lesions in the gastric body. Biopsy confirmed a well-differentiated neuroendocrine tumor (NET G1). EGD showed atrophy in the gastric body, but not in the antrum, indicating reverse atrophy typical of autoimmune gastritis (AIG). Based on these endoscopic findings, he was diagnosed as type I gastric NET (G-NET). Endoscopic submucosal dissection (ESD) was performed for both lesions. One lesion was intramucosal, with venous invasion. According to the current guidelines, type I G-NETs without muscularis propria (MP) invasion or lymph node metastasis can be managed without additional treatment. However, recent studies have suggested that venous invasion may be associated with an increased risk of lymph node metastasis. Therefore, careful long-term surveillance was required for him.

Source: Progress of Digestive Endoscopy

DOI: 10.11641/pde.107.1_73

Authors: Shirei Kobayashi, Tomoyuki Fujiwara, Yuko Okabe, Junji Kondo, Yoshihiro Furuichi, Hiroyuki Kato, Akinari Kakumoto, Ai Koyanagi, Hajime Kuroda, Koichiro Sato

Institutions: Tokyo Women's Medical University Adachi Medical Center, Tokyo Women's Medical University

Language: English

Topic: Neuroendocrine Tumor Research Advances

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7116892256

FWCI:

Cites: 4

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