Work

Necrotizing pneumonia and septic shock caused by Burkholderia cepacia in an immunocompetent adult

Year: 2025

Type: article

Abstract: We report the case of an immunocompetent adult presenting with acute febrile illness during a dengue outbreak in the Peruvian Amazon. The patient developed rapidly progressive respiratory compromise and hemodynamic instability, requiring admission to the intensive care unit for management of septic shock, necrotizing pneumonia, and multiorgan dysfunction. Despite full supportive care, he experienced refractory cardiorespiratory failure and died within 24 h of admission. Blood cultures later identified Burkholderia cepacia, and the association of bacteremia with necrotizing pulmonary involvement was consistent with cepacia syndrome. This case highlights a severe and uncommon presentation of B. cepacia infection in an immunocompetent host within a complex tropical epidemiological context.

Source: IDCases

DOI: 10.1016/j.idcr.2025.e02470

Authors: Jorge Luis Hurtado-Alegre, Jhonatan Mauricio Crispin-Ayala, Débora Rocío Mananita-Terrones, Jhosef Franck Quispe-Pari

Institutions: EsSALUD, Universidad Continental, Universidad Nacional del Centro del Perú

Language: English

Topic: Burkholderia infections and melioidosis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,370