Effects of Ozonized Oil on At‐Home Tooth Bleaching: A Double‐Blind Randomized Clinical Trial
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: OBJECTIVE: This double-blind, randomized clinical trial evaluated the effect of ozonized sunflower oil on tooth sensitivity, color change, and patient perception during at-home bleaching with 10% hydrogen peroxide. CLINICAL CONSIDERATIONS: Forty participants were randomly assigned to receive ozonized or nonozonized sunflower oil, applied in trays for 1 min after each bleaching session (30 min daily for 21 days). Sensitivity was assessed daily using visual and numerical scales. Tooth color was measured at baseline, 1 week, and 1 month after treatment using a spectrophotometer (ΔEab, ΔE00, ΔWID) and a visual shade guide (ΔSGUs). Patient perception was evaluated through Likert-scale questionnaires. CONCLUSIONS: Overall, 72.5% of participants experienced sensitivity, with no significant difference in intensity (p = 0.536) or duration (p = 0.256) between groups. Color changes were similar (p > 0.05), although ΔEab and ΔE00 values decreased at 1 month (p = 0.010 and p = 0.026). Ozonized oil had an unpleasant taste (p = 0.002) and odor (p = 0.010). The use of ozonized sunflower oil did not reduce bleaching-related sensitivity or enhance whitening effectiveness, and its poor sensory properties may limit patient acceptance.
DOI: 10.1111/jerd.70083
Authors: Murilo Guimarães Campolina, Lia Dietrich, Julia Marques Martins, Larissa Victoria Miranda Ubagai, Guilherme José Pimentel Lopes Oliveira, Ceci Nunes Carvalho, Hugo Lemes Carlo, Carlos José Soares, Gisele Rodrigues Silva
Language: English
Topic: Dental Erosion and Treatment
Subfield: Orthodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,030
Awards: G1426168670, G22113365, G29316538, G3690646728, G3768344506, G3899272551, G396010863, G6756993358, G6967842311, G7354331077, G7467166548, REDE MINEIRA EM SAÚDE ORAL E ODONTOLOGIA, G8188794456, INFLUÊNCIA DO USO PROLONGADO DO CARVÃO ATIVADO NAS PROPRIEDADES ÓPTICAS E MORFOLOGIA SUPERFICIAL DO ESMALTE DENTÁRIO E DE RESINAS COMPOSTAS
OpenAlex ID: W7117126796
