Work

The Future of Antibiotics and Artificial Intelligence: Some Thoughts from Discovery to Bedside

Year: 2025

Type: article

Abstract: Antibiotic discovery and antibiotic prescribing represent two domains that both stand to benefit from artificial intelligence (AI)-driven progress in the near future. In this article, we discuss these parallel advances and the potential future synergy between AI-enabled antibiotic discovery and AI-assisted antibiotic prescribing. Although multiple challenges remain before these two domains meaningfully converge, their integration could amplify the strengths of each: discovery pipelines generating broader, more diverse classes of antibacterial agents, and prescribing tools capable of matching these agents to individual patients with unprecedented precision. Such a scenario could transform antibiotic therapy by enabling AI-supported, patient-specific treatment decisions while reinforcing the principles of precision medicine and antimicrobial stewardship.

Source: Infectious Diseases and Therapy

DOI: 10.1007/s40121-025-01288-y

Authors: Daniele Roberto Giacobbe, Alessandra Agnese Grossi, Matteo Bassetti, Cesar de la Fuente-Nunez

Institutions: Ospedale Policlinico San Martino, University of Genoa, University of Insubria, University of Pennsylvania

Language: English

Topic: Antibiotic Use and Resistance

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $7,400