Cerebrospinal Fluid Holds the Key—Spinal Melioidosis Masquerading as Longitudinally Extensive Transverse Myelitis: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Case RepoRtthe onset of symptoms, he had sustained an injury with an open wound on his leg while playing football on a muddy ground, which resolved slowly over 1 month. IntroductIonMelioidosis is an infection caused by Burkholderia pseudomallei, especially in tropical regions.Of all melioidosis cases, only 4% presented as neuromelioidosis and have high morbidity and mortality.Initial presentation as myelitis is very rare, accounting for only 1% of neuromelioidosis.1,2 Here, a case of neuromelioidosis presenting as longitudinally extensive transverse myelitis (LETM) is reported, where the organism was isolated only from cerebrospinal fluid (CSF). case descrIptIonA 44-year-old gentleman from Kerala, a South Indian state, presented with a 2-day history of acute onset of low back pain, weakness of both lower limbs, sensory impairment till the level of the umbilicus, and bladder involvement in the form of urinary retention over a 2-day duration.He was treated outside with pulse intravenous methyl prednisolone, suspecting demyelination since the magnetic resonance imaging (MRI) of the dorsal spine showed a long-segment, T2-hyperintense lesion extending from T10 to conus.He was referred to our center as there was no clinical improvement.He had no other systemic symptoms or fever, and does not have any medical comorbidities.Two months prior to 1-
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7117148956