Work

Primary Hepatic Leiomyosarcoma Presenting as a Multiloculated Cystic Mass: A Case Report and Review of Literature

Year: 2025

Type: article

Abstract: Primary hepatic leiomyosarcoma (PHL) is a rare malignant mesenchymal tumor representing a small fraction of primary hepatic cancers. Due to its nonspecific clinical and radiologic presentation, it is often misdiagnosed. We present the case of an 82-year-old male who presented with altered mental status and was found to have a multiloculated cystic mass in the liver, initially suspected to be a hepatic abscess. Histopathological evaluation of the mass revealed a diagnosis of PHL. Despite palliative chemotherapy, the patient succumbed to metastatic disease within two months. PHL is a rare neoplasm with varied clinical manifestations. The unusual cystic presentation, as seen in this case, highlights the importance of maintaining a broad differential when evaluating hepatic masses.

Source: Cureus

DOI: 10.7759/cureus.99966

Authors: Akhila Aravind, Navdeep Kaur, Youssef Al Hmada, Anita Choudhary, Satyapal Chahar

Institutions: University of Mississippi Medical Center, Mayo Clinic

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7117161593