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Surgical treatment of a patient with severe aortic stenosis and hereditary factor XI deficiency

Year: 2025

Type: article

Abstract: Surgery is the only effective treatment for severe aortic stenosis. Previously, valve replacement was only performed under cardiopulmonary bypass. Minimally invasive transcatheter aortic valve implantation (TAVI) is currently available for high-risk patients, including elderly ones. However, there is a risk of hemorrhagic complications even in minimally invasive procedures. In general population, the incidence of bleeding requiring transfusion after TAVI is 6—9%. The risk of bleeding is even higher in patients with clotting disorders. We present successful management of a patient with hereditary factor XI deficiency who required surgical treatment for severe symptomatic aortic stenosis.

Source: Russian Cardiology Bulletin

DOI: 10.17116/cardiobulletin20252004188

Authors: E.V. Kozlova, O.S. Bulkina, N.I. Zozulya, V.V. Lopukhova, A.E. Komlev, A.S. Kolegaev, N.S. Maslennikova, T.E. Imaev, Yu.A. Karpov

Institutions: National Medical Research Center of Cardiology, National Medical Research Center for Hematology

Language: English

Topic: Cardiac Valve Diseases and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7117237017

FWCI:

Cites: 17

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