Work

Obesity and Its Role in Carcinogenesis: Molecular Mechanisms and Clinical Implications

Year: 2025
Type: article
Abstract: incidence.Postmenopausal women with obesity face a 20-60% elevated risk of developing breast cancer compared to those with normal BMI.8,9 The IARC reviewed over 1,000 studies, confirming that excess adiposity is linked to cancers such as endometrial, esophageal, liver, kidney, pancreas, breast (postmenopausal), and thyroid cancers.10 For example, severe obesity can raise endometrial cancer risk up to seven times and esophageal cancer risk nearly five times.A large Spanish cohort study also linked obesity with 18 different malignancies.11 review results Epidemiological EvidenceNumerous cohort and case-control studies support a positive correlation between obesity and increased cancer
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: bronze
OpenAlex ID: W7117254690
FWCI:
Cites: 23
Cited by:
Related to: