Work

RNA Interference in Plant Interactions with Pathogenic Microorganisms: A Weapon or a Liability?

Year: 2025

Type: article

Abstract: The RNA interference machinery is crucial for regulating the activity of both native and foreign genes across all eukaryotes. The core protein families involved in this process are Dicer-like, Argonaute, and RNA-dependent RNA polymerase. However, plants exhibit remarkable diversity within each family and extensively use RNA interference mechanisms in their intricate immune responses. This review examines the role of RNA interference in plant interactions with various pathogens, including viruses, viroids, fungi, oomycetes, and bacteria. Plant diseases cause an estimated $220 billion in annual damage, with microorganisms accounting for approximately $150 billion. Hence, the focus is on the most severe plant diseases, specifically those caused by fungi and viruses. Additionally, recent biotechnological advancements are discussed, with an emphasis on the application of RNA interference for the development of novel plant defence strategies.

Source: Current Issues in Molecular Biology

DOI: 10.3390/cimb48010021

Authors: Artemii Ivanov, Tatiana Golubeva

Institutions: Novosibirsk State University, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Immanuel Kant Baltic Federal University

Language: English

Topic: Plant Virus Research Studies

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: gold

Estimated APC paid: $2,654