Work

Chemoselectivity in the cationic Phospha-Wittig reaction: accessing phosphorus heterocycles, phosphaalkenes, and their annulated [4 + 2] dimers

Year: 2025

Type: article

Abstract: . Computational studies reveal that the operative mechanism of this transformation involves a Phospha-Diels-Alder step followed by an acid-base-catalytic proton transfer, which is calculated to be energetically more accessible than the classical [2 + 2] dimerisation.

Source: Chemical Science

DOI: 10.1039/d5sc08693k

Authors: Philipp Royla, Kai Schwedtmann, Rosa M. Gomila, Antonio Frontera, Jan J. Weigand

Institutions: Technische Universität Dresden, Universitat de les Illes Balears

Language: English

Topic: Phosphorus compounds and reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Deutsche Forschungsgemeinschaft, Technische Universität Dresden, Agencia Estatal de Investigación

Awards: G1167523120, G135608027, G4478849203