Work

Informatics in allergology

Year: 2025

Type: article

Abstract: Allergic diseases have a high prevalence among populations worldwide affecting nearly 10-30% individuals. The gap between allergy incidence and currently available treatment options needs to be filled. Computational approaches aim to bridge this gap by utilizing and annotating existing knowledge on allergic proteins along with providing novel predictions and insights. In silico methods can be employed for identifying several factors pertaining to allergens such as structural characterization, determination of allergenicity of proteins, prediction of epitope sites, interactions with antibodies and immune receptors as well as in design of immune therapeutics. This review summarises the vital role of informatics in allergology and the exhaustive approaches available that assist in identification of novel aspects related to allergens.

Source: Allergy medicine.

DOI: 10.1016/j.allmed.2025.100091

Authors: Mansi Pandit, N. Latha

Institutions: University of Delhi, Bennett University

Language: English

Topic: vaccines and immunoinformatics approaches

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,300