Analysis of the Characteristics of Measles Virus D8 Genotype Based on the Nucleoprotein (N-450) Gene Region - Gansu Province, China, 2024.
Year: 2025
Type: article
Abstract: What is already known about this topic?: Measles is a common infectious disease, and the global health community is working to eliminate it. However, recent measles outbreaks in several countries have posed challenges for China, which is close to eliminating the disease. What is added by this report?: In Gansu Province, in 2024, the predominant measles virus (MeV) strains were found to be genotype D8, forming two distinct clusters. Notably, mutations within one of these clusters, at a critical diagnostic primer-binding site, could potentially affect the sensitivity of detection methods. What are the implications for public health practice?: The findings suggest imported virus transmission. Sustaining vaccination programs in key areas and enhancing sensitive virus surveillance are critical for measles elimination efforts.
Source: PubMed
Authors: Huan Wei, Hui Zhang, Jianhua Chen, Shu Liang, Maoxing Dong, Biao Wang, Miao Wang, Xiaoshu Zhang
Language: English
Topic: Virology and Viral Diseases
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7117370893
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