Work

Synthetic biology for phytohormone production

Year: 2025

Type: review

Abstract: Phytohormones are compounds produced by plants that can control the processes of plant development and are involved in defense mechanisms. They can serve as sustainable enhancers for plant growth and are also better alternatives to agrochemicals because of their bio-based nature and optimal safety profile towards mammalian cells. Although phytohormones are essential for plant growth, they are naturally synthesized by plants in varying quantities, influenced both by environmental and genetic factors. The synthesis of phytohormones, however, faces several hurdles, including challenges in optimizing the production process as well as difficulties in the extraction of these compounds for downstream applications. In this review, we critically evaluate synthetic biology approaches for phytohormone production, which provides a sustainable method for the production of important phytohormones including auxin, gibberellin (GA), and salicylic acid (SA). These three compounds are highly significant for the agricultural industry because of their widespread utilization.

Source: Current Opinion in Chemical Biology

DOI: 10.1016/j.cbpa.2025.102649

Authors: Pattarawan Intasian, Ninlapan Kimprasoot, Duangthip Trisrivirat, Pimchai Chaiyen

Institution: Vidyasirimedhi Institute of Science and Technology

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: hybrid

Estimated APC paid: $4,510