Year: 2025
Type: article
Abstract: QUESTION: An 81-year-old male patient was referred for evaluation of a pancreatic mass.Computed tomography revealed a 4-cm mass located in the pancreatic tail accompanied by multiple hepatic metastatic lesions.Given that the patient's Eastern Cooperative Oncology Group (ECOG) performance status is 0-1, what would be the appropriate treatment strategy?ANSWER: In the Korea clinical setting, FOLFIRINOX and gemcitabine plus nab-paclitaxel (GEM-NABP) regimens can be used as first-line treatments.As the patient's general condition was favorable, systemic chemotherapy was initiated with the modified FOLFIRINOX regimen.Followup response evaluation showed a partial response, and chemotherapy is currently ongoing.compared with NALIRIFOX (hazard ratio [HR], 1.45; 95% CI, 1.22-1.73;p < 0.001).In a network meta-analysis, GEM-JDCR
Author: Jun Hyung Lee
Institutions: Chosun University, Chosun University Hospital
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7117478268