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Multiomics Profiling Unveils Key Genes and Metabolites Involved in the Salt Tolerance of Gossypium hirsutum

Year: 2025

Type: article

Abstract: BACKGROUND: Salt stress is a primary abiotic constraint on cotton growth, significantly impairing yield and fiber quality. METHODS: , we performed transcriptomic and metabolomic profiling at multiple time points following salt treatment. RESULTS: We identified 33,975 differentially expressed genes (DEGs), with significant enrichment in pathways related to plant hormone signal transduction, amino acid metabolism, and starch and sucrose metabolism. K-means clustering grouped the DEGs into six expression modules corresponding to distinct response stages. Additionally, UPLC-MS analysis identified 6292 metabolites-spanning lipids, carbohydrates, and amino acids-and revealed substantial metabolic reprogramming with increasing stress duration. An integrated multiomics analysis highlighted the ABC transporter and starch and sucrose metabolism pathways as key regulatory modules for salt tolerance and identified critical genes within them. CONCLUSIONS: under salt stress, offering valuable insights for understanding the molecular mechanisms of salt tolerance.

Source: Genes

DOI: 10.3390/genes17010022

Authors: Zheng Weng, Fan Wang, Xin Wei, Lianjia Zhao, Wei Wang, Jianfeng Lei

Institutions: Xinjiang Agricultural University, Xinjiang Academy of Agricultural Sciences

Language: English

Topic: Plant Stress Responses and Tolerance

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: gold

Estimated APC paid: $3,137