Opioid Prescribing in Opioid-Naïve and Opioid-Exposed Mechanically Ventilated Medically Critically Ill Patients
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: Characterize opioid prescribing patterns in the ICU and post-hospital discharge in invasively mechanically ventilated (IMV) opioid-naïve and opioid-exposed patients. Design: Single-center, retrospective cohort study. Setting: Tertiary academic medical center. Patients, participants: Patients requiring IMV admitted to the MICU. Interventions: None. Main outcomes measure(s): Difference in opioid prescriptions at discharge from the hospital and opioid use during IMV between groups. Results: A total of 85 patients were included, 60 (70.6%) were opioid-naïve and 25 (29.4%) were opioid-exposed prior to admission. Five (8.3%) opioid-naïve and 16 (64.0%) opioid-exposed were prescribed opioids on discharge ( P < 0.001). Median morphine milligram equivalents (MME) per day during IMV did not differ between groups. Conclusions: Although opioid discharge prescribing was relatively uncommon among medical ICU patients who were opioid-naïve prior to admission, areas to evaluate and optimize opioid prescribing during IMV and at discharge were identified.
Source: Hospital Pharmacy
Institutions: Concordia University Wisconsin, Medical College of Wisconsin
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7117546715