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Bioactive Potential of Six Edible Mushrooms: Antimicrobial, Antioxidant, and Cytotoxic Properties

Year: 2025

Type: article

Abstract: In the present study, antimicrobial, antibacterial, and cytotoxic effects of methanol and acetone extracts obtained from the edible mushroom species of Boletus edulis, Chanterellus cibarius, Craterellus cornucopioides, Agaricus bisporus, Pleurotus ostreatus, and Morchella esculenta were determined in vitro. The B. edulis methanol extract showed the highest 1,1-diphenyl-2-picrylhydrazy (DPPH) scavenging effect at 1mg mL-1 concentration with 34.68 ± 1.56 %. It was determined that the total phenolic content of the extracts varied between 27.22 ± 2.29 - 16.67 ± 0.88 µg GAE mg-1 extract. The findings suggest that the extracts have varying antimicrobial effects on pathogenic bacteria. 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) cell viability test was performed to investigate the cytotoxic effects of the extracts. Cytotoxicity studies demonstrated that C. cibarius selectively decreased cancer cell viability, while C. cornucopioides, P. ostreatus, and A. bisporus exhibited proliferative effects on cancer cells.

Source: Türk doğa ve fen dergisi :/Türk doğa ve fen dergisi

DOI: 10.46810/tdfd.1727285

Authors: Özge Özcan, Gamze Altıntaş Kazar, Elif Gezer Aslan

Institutions: Kırklareli University, Kırıkkale University, Trakya University, Trakia University

Language: English

Topic: Fungal Biology and Applications

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDGs: Zero hunger, Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7117551288

FWCI:

Cites: 38

Cited by:

Related to: 10