Surgical outcomes of patients complaining of moderate tricuspid regurge with replacement mitral valve regurgitation
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Background and aim Tricuspid valve (TV) repair may be necessary if the valve is incompetent, resulting in leakage, or if it fails to open and close properly. Surgical intervention might be required to correct congenital defects or to address valve damage caused by endocarditis. This study aimed to evaluate the progression of TV dysfunction following mitral valve replacement in patients presenting with mitral valve regurgitation and concomitant mild to moderate TV regurgitation. Patients and methods This prospective research was performed on 50 patients of both sexes, with moderate functional TR secondary to rheumatic mitral valve pathology. The patients were randomized into two groups. The repair group included 25 patients who underwent tricuspid repair with mitral valve replacement, and the nonrepair group included 25 patients, also, but without tricuspid repair with mitral valve replacement. Results Postoperative tricuspid regurgitation murmur and left ventricle ejection fraction (LVEF) were significantly less in the repair group than in the nonrepair group ( P <0.001). TV regurgitation was markedly different at immediately postoperative, 3, 6, and 12 months in repair groups than in nonrepair groups ( P <0.001). Gradient TV was significantly lower immediately postoperative, 3, 6, and 12 months in the repair group than the nonrepair group ( P <0.001). Conclusion Concomitant TV repair during mitral valve regurgitation improved right heart function and reduced tricuspid regurgitation severity, despite a transient reduction in LVEF. The observed LVEF reduction likely reflects methodological variability rather than true hemodynamic compromise, supporting the overall neutrality of this outcome.
Source: Al-Azhar Assiut Medical Journal
Authors: Alaa E.G. El Karem, Adel M. Khalaf, Amer Y. Mohamed, Farouk M. Ragab
Institution: Al-Azhar University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $250
OpenAlex ID: W7117584564