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Focal Epilepsy with subcortical grey matter heterotopia

Year: 2025

Type: article

Abstract: A 38-year-old man with recurrent bilateral tonic–clonic seizures since 2018 presented in January 2025 for further evaluation. His seizures occurred 1–2 times per month and were commonly precipitated by sleep deprivation or exposure to cold water. Episodes were accompanied by tongue biting, post-ictal confusion, and amnesia. He had no significant medical or family history, and neurological examination was unremarkable. MRI of the brain demonstrated nodular subcortical grey-matter heterotopia adjacent to the right putamen and a similar lesion in the left corona radiata. The EEG recorded during wakefulness was normal. Laboratory tests were notable only for elevated total cholesterol. Findings were consistent with focal epilepsy secondary to subcortical grey-matter heterotopia.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18091814

Author: Kyaw Thura1*, Naing Ko Soe2, Myint Thein Naing3, Hein Zaw Zaw4, Aung Myo Oo 5 ,Su Su San6, Pyi Thar7, Myo Min Zin 8 ,Wai Moe Thein 9 , Ohnmar Saw10, Nwe Nwe Win11

Language: English

Topic: Epilepsy research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7117690150

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