Work

Breakthroughs in Solubility Optimization for Pediatric Drug Formulations

Year: 2025
Type: article
Abstract: Formulating drugs for pediatric patients is more complex than for adults due to the diversity within this group. Solubility of active pharmaceutical ingredients (APIs) presents specific challenges, since children have unique physiological traits—smaller stomach volume and immature digestive systems—that affect absorption, metabolism, and overall drug effectiveness. ‏Oral formulations must consider drug sensitivity, swallowing difficulties, and compliance. Taste, ease of administration, and patient acceptance strongly influence therapeutic outcomes and safety. Ensuring children take medication as directed is often as important as the formulation itself. ‏To address these issues, solubility enhancement technologies have advanced
Language: English
Open Access status: diamond
OpenAlex ID: W7117705109
FWCI:
Cites: 123
Cited by:
Related to: