Work

Artificial Womb Technology for Extremely Premature Neonates: Preclinical Neurodevelopmental Outcomes

Year: 2025

Type: article

Abstract: In this narrative review, we examine current neurological and neurodevelopmental outcomes associated with extreme prematurity, specifically in infants born between 22 and 24 weeks of gestational age. In addition, we explore the scientific and clinical rationale for the development of artificial womb technology and provide an overview of the current state of the art in preclinical models. For each model, we review and analyze the neurological outcomes, including structural, developmental, and functional outcomes, evaluating their limitations in anticipation of imminent clinical translation.

Source: Children

DOI: 10.3390/children13010047

Authors: Felix R. De Bie, Chelsea J. Zhang, Sharla M. Rent, Jeffrey B. Russ, Kevin Ig-Izevbekhai, Ryan M. Antiel

Institutions: Duke University, Duke Medical Center

Language: English

Topic: Infant Development and Preterm Care

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896