Work

Relationship Between Clinical Factors and the Risk of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage: An Exploratory Analysis

Year: 2025

Type: article

Abstract: Background/Objectives: Cerebral subarachnoid hemorrhage (SAH) from ruptured aneurysms poses significant morbidity and mortality risks. Among survivors, cerebral vasospasm can develop, increasing complications. This study investigates the relationship between blood parameters and the risk of vasospasm. Methods: We analyzed clinical data from patients with SAH—both with and without vasospasm—and healthy controls. Statistical analyses, including Spearman’s rank correlation and univariate analysis, were conducted. Results: Significant differences were observed between patients with and without vasospasm. Elevated white blood cell counts, a higher neutrophil-to-lymphocyte ratio, and lower platelet counts showed a significant association with symptomatic vasospasm. Younger age and female gender were associated with a higher risk. Conclusions: These preliminary findings highlight the importance of specific blood parameters and demographic factors in assessing the risk of cerebral vasospasm in SAH patients, supporting early risk stratification and monitoring to improve outcomes; however, these results require validation in larger cohorts.

Source: Life

DOI: 10.3390/life16010059

Authors: Máté Czabajszki, Attila Garami, Péter Csécsei, Béla Viskolcz, Csaba Oláh, Csaba Váradi

Institutions: University of Miskolc, Borsod-Abaúj-Zemplén Megyei Kórház és Egyetemi Oktató Kórház, University of Pecs

Language: English

Topic: Intracranial Aneurysms: Treatment and Complications

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137