Year: 2025
Type: article
Study design: Systematic Review
Abstract: This systematic review evaluates the recent advancements over the past decade in the application of laser Doppler flowmetry (LDF) for measuring microcirculation and predicting outcomes in intestinal ischemia. A comprehensive analysis of experimental and clinical studies highlights the potential of LDF as a sensitive tool for assessing tissue viability and delineating ischemic boundaries. While numerous investigations demonstrate its promising diagnostic utility, significant variability in results and the lack of standardized thresholds limit widespread clinical adoption. The review emphasizes the need for further large-scale, multicenter studies to establish standardized parameter cutoff values and to optimize the integration of LDF with complementary imaging modalities. Overall, LDF remains a promising technique for enhancing the diagnosis and management of intestinal ischemia, contingent upon future validation and methodological standardization.
Source: Russian Open Medical Journal
Institution: Saratov State Medical University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7117743301