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Posterior Reversible Encephalopathy Syndrome as an Under-Recognized Neurological Complication of Multisystem Inflammatory Syndrome in Children: A Case from Indonesia

Year: 2025

Type: article

Abstract: Posterior Reversible Encephalopathy Syndrome (PRES) is a rare but potentially reversible neurological manifestation associated with Multisystem Inflammatory Syndrome in Children (MIS-C). We report an eight-year-old boy who developed PRES secondary to MIS-C following asymptomatic SARS-CoV-2 exposure. The patient presented with fever, seizures, decreased consciousness, and visual disturbances. MRI revealed characteristic bilateral parieto-occipital and posterior temporal cortical–subcortical hyperintensities, while CT scans were normal. The patient achieved full neurological recovery with corticosteroid therapy, blood pressure control, and supportive management. This case underscores the importance of early MRI in detecting PRES when clinical or CT findings are inconclusive, emphasizing the need for heightened awareness among pediatric clinicians to prevent irreversible neurological sequelae.

Source: COVID

DOI: 10.3390/covid6010008

Authors: Ido Narpati Bramantya, Ratna Sutanto, Callistus Bruce Henfry Sulay, Gilbert Sterling Octavius

Institution: Pelita Harapan University

Language: English

Topic: Neurological Complications and Syndromes

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,207