Work

MIOLO Standard Formula v2.5 -- Calibrated IOL Power Calculation with Physics-Informed Machine Learning

Year: 2025

Type: article

Abstract: MIOLO Standard v2.5: Calibrated intraocular lens (IOL) power calculation formula using physics-informed machine learning. This version achieves 280/280 (100%) concordance with Barrett Universal II across 28 strategically selected validation cases spanning AL 21.5-29.0mm, K 39.9-46.9D, ACD 2.5-3.8mm. Key innovations include: (1) 6-term Barrett calibration layer with Kavg*ACD interaction and ACD quadratic modeling, (2) dampening mechanism for long myopic eyes with steep corneas, (3) fade-based short eye protection preserving superior hyperopic performance. Base model (v2.2) coefficients remain unchanged. Formula MLV transformation constitutes protected intellectual property. Supersedes v2.2 (DOI: 10.5281/zenodo.18099603).

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18099602

Author: miolo, bruno

Institution: Universidade Federal de São Paulo

Language: English

Topic: Intraocular Surgery and Lenses

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7117780106

FWCI:

Cites:

Cited by:

Related to: