Work

An antioxidant and antibacterial octyl gallate sustained-release ointment for periodontitis treatment

Year: 2025

Type: article

Abstract: growth, and reduced ROS in macrophages. In a rat periodontitis model, OG-Ointment significantly reduced alveolar bone resorption, decreased ROS and inflammatory cytokines, and exhibited good biocompatibility. These findings suggest that OG-Ointment is a promising non-antibiotic adjunctive therapy for periodontitis, combining dual antioxidant and antibacterial functions with sustained release.

Source: iScience

DOI: 10.1016/j.isci.2025.114550

Authors: Han-Ping Wang, Chen-Yu Xu, Wen Su, Yin-Song Wang, Yue Wang, Ming-Xin Cao

Institution: Tianjin Medical University

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240