Work

Effects of Neurorehabilitation Program on Cognitive Function in Cancer Survivors: A Meta-Analysis

Year: 2025

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: Purpose: Cancer survivors frequently experience chemotherapy-related cognitive impairment (CRCI), which contributes to difficulties in memory and thinking. Effective rehabilitation programs are therefore essential to help survivors manage CRCI and improve quality of life.Methods: A systematic search of CINAHL, Cochrane Library, PubMed, and Embase identified studies that met predefined criteria based on participant, intervention, comparison, outcome, and study design. The primary outcome was analyzed using a random-effects model with statistical significance set at p<.05. Heterogeneity was assessd using the I2 statistic.Results: Of 10,288 screened studies, 10 met the inclusion criteria. Neurocognitive rehabilitation programs showed a small but statistically significant overall effect on cognitive function (Hedges' g=0.45, 95% CI=0.29~0.61, Z=5.57, p<.001). Subgroup analyses indicated significant effects for both overall cognitive function and specific cognitive domains (p<.001).Conclusion: Neurorehabilitation programs are effective in enhancing cognitive function among cancer survivors, with optimal outcomes observed in interventions delivered for one to two hours per session over five to seven weeks.

Source: Journal of Korean Academy of Psychiatric and Mental Health Nursing

DOI: 10.12934/jkpmhn.2025.34.4.425

Authors: Sangjin Ko, Shin-Jeong Park

Institution: Kyungil University

Language: English

Topic: Cancer-related cognitive impairment studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea