Work

The Pace of Cognitive Aging in Older Adults Without a Neurocognitive Disorder

Year: 2025

Type: article

Abstract: The pace of cognitive change without a neurocognitive disorder is one of the major questions in cognitive aging. The Children of the Depression Age (CODA) cohort of the Health and Retirement Study (HRS) is ideal for studying cognitive aging because it has a long follow-up (22 years) and a narrow age range at baseline (67-74 years). We analyzed data on delayed word recall performance in HRS-CODA (N = 2,295), gathered every other year during the follow-up period. Using latent growth curve modeling and treating delayed recall as a categorical outcome, we found a quadratic model showed better fit to the data than a linear model, with no strong evidence for a practice and retest effect. When calculating the pace of normative aging, our results suggested normative (defined as the absence of a dementia diagnosis over the follow-up period) memory decline is about -0.05 standard deviations per year (SD/y), but is better characterized by age specific estimates of -0.04 SD/y, -0.10 SD/y, and -0.15 SD/y for individuals in their 70s, 80s, and 90s, respectively. These results would suggest that memory decline, in the absence of a recognized dementia and without a confounding of baseline age differences and longitudinal age changes, would be present but almost imperceptible to an individual in their eighth decade, but noticeable in their ninth and quite impairing in their tenth decade.

Source: Innovation in Aging

DOI: 10.1093/geroni/igaf122.537