Work

Sex differences in life expectancy in dementia, mild cognitive impairment, and subjective cognitive decline

Year: 2025

Type: article

Abstract: Introduction It is unclear how dementia affects loss in life expectancy (LE). In this registry-based study, we aimed to study sex differences in LE and loss in LE in dementia, mild cognitive impairment (MCI), and subjective cognitive decline (SCD). Methods 16,358 patients diagnosed with dementia, MCI or SCD from the Norwegian registry of persons assessed for cognitive symptoms (NorCog) during 2009-2022 were included and followed up for mortality. Sex differences in LE, and loss in LE, were predicted using flexible parametric survival models and sex specific mortality in the general population as reference. Results Women with dementia had the largest loss in LE; 17 years loss at 60 years, correspondingly men lost 13.5 years. Similar patterns were observed for MCI and dementia subtypes. Discussion Women with dementia or MCI had larger loss in LE compared to men with these diagnoses.

Source: Innovation in Aging

DOI: 10.1093/geroni/igaf122.3190

Authors: Rachel Amland, Bjorn Heine Strand

Institutions: University of Oslo, Norwegian Institute of Public Health

Language: English

Topic: Dementia and Cognitive Impairment Research

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: gold

Estimated APC paid: $3,977