Polyphenols as Epigenetic Modulators of Health: A Holistic Approach to the Therapy and Prevention of Chronic Diseases
Year: 2025
Type: article
Abstract: BACKGROUND: The rising prevalence of chronic diseases, including cancer, metabolic disorders, neurodegenerative, and cardiovascular conditions, presents a growing challenge to modern medicine and public health. AIM: This article investigates the potential of polyphenols as modulators of epigenetic mechanisms in the context of chronic disease. METHODS: A comprehensive review of scientific literature was conducted, with emphasis on key epigenetic processes such as DNA methylation, histone modifications, and microRNA regulation. RESULTS: Polyphenols like resveratrol, curcumin, quercetin, and catechins exert protective actions by modulating gene expression, counteracting harmful epigenetic changes, and supporting cellular health. CONCLUSION: Advancing our understanding of how polyphenols influence epigenetic pathways may lead to innovative therapeutic strategies combining conventional and personalized approaches.
Source: La Tunisie Médicale
Author: Sara Gheribi
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7118080367
FWCI:
Cites:
Cited by:
Related to: