Work

Takotsubo Syndrome – Current Knowledge and Clinical Challenges

Year: 2025

Type: article

Abstract: "Broken heart syndrome" is one of several terms used to describe Takotsubo syndrome. This name refers to the fact that severe emotional or physical stress is considered to be a triggering factor for the disease. Takotsubo syndrome is an acute cardiac condition characterized by reversible ventricular dysfunction and various cardiac wall-motion abnormalities. It presents with a symptom profile that closely resembles acute coronary syndrome. Therefore, it is usually underdiagnosed, especially in patients who have co-existing coronary artery disease. Despite its transient nature, the condition may be associated with various life-threatening complications including arrhythmias, acute heart failure, cardiogenic shock, ventricular thrombus and risk for cerebrovascular events. Purpose: The aim of this review is to present the current state of knowledge about Takotsubo syndrome and to highlight aspects that require further investigation and systematization. Materials and Methods: A literature review was conducted from the PubMed database, covering studies from 2015-2025. Key phrases such as “Takotsubo Syndrome”, “Broken Heart Syndrome”, “Stress Cardiomyopathy” were used. Selected papers were analyzed and evaluated for conclusions. Conclusions: Takotsubo syndrome remains incompletely understood, with significant gaps in its diagnostic criteria, therapeutic management, and strategies for preventing recurrence. Further research, including large-scale clinical trials and comprehensive meta-analyses, is essential to establish evidence-based guidelines and improve patient outcomes.

Source: International Journal of Innovative Technologies in Social Science

DOI: 10.31435/ijitss.4(48).2025.4377