Year: 2025
Type: article
Abstract: INTRODUCTION: Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare malignant tumor that develops in the nasal cavity. It accounts for only 1.2% of malignant nasosinus tumor and arises from the olfactory epithelium. METHODS: This retrospective study presents olfactory neuroblastoma cases treated in our ENT department over a period of 36 years, from January 1986 to December 2023. RESULTS: The study results indicate that the series consisted of 10 cases of olfactory neuroblastoma, with seven females and three males, and a mean age of 40 years. Based on the Kadish classification, 6 cases were classified as stage B, 3 as stage C, and 1 as stage D. Of the 8 patients who underwent surgery, 6 patients also received radiotherapy, while 2 cases were inoperable. After surgery followed by radiotherapy, complete remission was observed in 3 cases. Tumor progression was observed in 2 cases, after 8 and 3 months respectively and tumour recurrence was observed in one patient. CONCLUSION: Although the imaging features of olfactory neuroblastoma are non-specific, there are patterns of disease that should strongly suggest and stage this disorder. This is fundamental for surgical planning.
Source: La Tunisie Médicale
Institutions: Hôpital Farhat Hached, University of Sousse
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7118093718
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