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Correction: Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia

Year: 2026

Type: erratum

Abstract: The original version of this Article contained an error in Fig. 5 K, in which the figure incorrectly uses the immunohistochemistry image of leptin, which should be Ob-Rb. The original Fig. 5 and accompanying legend appear below. Fig. 5 Hypoxia resulted in decreased leptin, ob-Rb, and HIF1α protein levels in rat myocardial tissues. ( A ) Plasma leptin. ( B ) Western blot analysis of HIF1α, leptin, and Ob-Rb in left ventricular myocardial tissues. ( C – E ) Quantification of HIF1α, leptin, and Ob-Rb protein expression in left ventricular myocardial tissues. ( F ) Western blot analysis of HIF1α, leptin, and Ob-Rb in right ventricular myocardial tissues. ( G – I ) Quantification of HIF1α, leptin, and Ob-Rb protein expression in left ventricular myocardial tissues. The protein expression levels were normalized to those of β-Tubulin. ( J , K ) Immunohistochemistry of leptin and Ob-Rb in left and right ventricular myocardial tissues. n = 6. Data are presented as mean ± SEM. The p values are shown on the top of compared group by two-tailed unpaired t-test (for normally distributed data) or Mann–Whitney U test (for nonnormally distributed data). Full size image

Source: Scientific Reports

DOI: 10.1038/s41598-025-30890-w