Work

Case Report: A case of cervical burkitt lymphoma and literature review

Year: 2026

Type: article

Abstract: Primary cervical Burkitt’s lymphoma (BL) is an extremely rare malignancy. This report describes the case of a 55-year-old woman admitted to the hospital with irregular vaginal bleeding. Histologically, the tumor cells demonstrated infiltrative growth, relatively uniform basophilic cytoplasm. Immunohistochemical analysis revealed positivity for B-cell markers (CD20, CD79α, etc.), with MYC expression in approximately 80% of cells, fluorescence in situ hybridization staining showed positivity for MYC translocation and molecular testing confirmed IG rearrangement. The diagnosis of Burkitt’s lymphoma is based on its distinctive histological morphology in combination with immunohistochemistry and molecular testing.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1696219

Authors: Sen Miao, Yue Bai, Hua Hao

Institutions: Affiliated Hospital of Jining Medical University, Tongji University, Yangpu Hospital of Tongji University

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801