Work

Physico-mechanical reinforcement and antimicrobial efficiency of green-synthesized Ca/bentonite/chitosan nanocomposites

Year: 2026

Type: article

Abstract: The need to balance biomaterials' mechanical and biological properties is driving the development of scaffolds for tissue engineering applications. A scaffold composed of Eggshell calcium (Ca), exfoliated bentonite (EXF-BE), and Chitosan (CS) was synthesized and studied as a bone tissue scaffold. The highest value of the surface area was 134.6 m²/g for the Ca/EXF-BE/CS with an average pore width of 44.5 Å. The mechanical properties of EXF-BE were enhanced with Ca and CS addition, which is clear in the values of ultimate tensile strength (σ uts ) 15.38 MPa, 16.19 MPa, and 17.84 MPa; Toughness 1.435± 0.23 MJ/m 3 , 1.713 MJ/m 3 , 2.067 MJ/m 3 , and strain at breakdown of about 28.5, 28.69 ± 0.3%, and 30.1 ± 0.33% for EXF-BE, Ca/EXF-BE, and Ca/EXF-BE/CS, respectively. Antimicrobial properties, assessed by the disc diffusion method, showed inhibition zones of 27.13, 21.25, 19.25, and 20.88 mm against E. coli and S. aureus, demonstrating promising multifunctional properties.

Source: Beni-Suef University Journal of Basic and Applied Sciences

DOI: 10.1186/s43088-025-00725-8

Authors: Islam Saad, Wael A. Fathy, Rafat M. Amin, S.I. El-Dek

Institutions: Beni-Suef University, King Abdulaziz University

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7118179229