Work

Co-Morbid Insomnia and Sleep Apnea and Obstructive Sleep Apnea: Comparative Analysis of Clinical and Polysomnographic Features

Year: 2025

Type: article

Abstract: Objectives: This study aimed to investigate and compare the clinical characteristics of obstructive sleep apnea (OSA) and co-morbid insomnia and sleep apnea (COMISA) using sleep questionnaires and polysomnographic findings. Methods: We enrolled 850 patients who completed sleep questionnaires and underwent level 1 polysomnography (PSG) with an apnea-hypopnea index (AHI) ≥15. Patients were classified as OSA if the Insomnia Severity Index (ISI) <15, or as COMISA if ISI ≥15. Demographic and clinical characteristics, as well as PSG parameters, were compared between the groups. Results: The COMISA group showed greater daytime sleepiness, lower sleep quality with increased sleep fragmentation, and longer sleep latency than the OSA group, as measured by the Epworth Sleepiness Scale, the Pittsburgh Sleep Quality Index, and PSG (p<0.05). The OSA group reported more frequent snoring and more severe sleep apnea, with a higher AHI than the COMISA group (p<0.05). The COMISA group underestimated their sleep quality, while the OSA group had less insight into sleep problems. Conclusions: Patients with COMISA and OSA have different subjective and objective sleep profiles and perceptions of sleep. Understanding each characteristic and properly differentiating between COMISA and OSA in the clinic for tailored management is needed.

Source: Journal of Sleep Medicine

DOI: 10.13078/jsm.250027

Authors: Hyoeun Bae, Yi-Seul Choo, Suin Lee, Eun Yeon Joo

Institutions: Ewha Womans University Seoul Hospital, Samsung Medical Center, Sungkyunkwan University

Language: English

Topic: Obstructive Sleep Apnea Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Samsung, Samsung Medical Center, Sungkyunkwan University