Efficient synthesis of functionalized hydrofurans and pyrrolsemploying hexachloroacetone
Year: 2025
Type: article
Abstract: Isocyanides react smoothly with dimethyl acetylenedicarboxylate in the presence of hexachloroacetone to produce dimethyl 5-[alkyl(aryl)imino]-2,2-bis(trichloromethyl)-2,5-dihydro-furan-3,4-dicarboxylates in high yields. When the reaction was performed in the presence of dibenzoylacetylene, 3-benzoyl-1-alkyl-4-chloro-5- hydroxy-5-phenyl-1,5-dihydro-2H-pyrrol-2-ones were obtained.
Author: IAU
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W7118249285
FWCI:
Cites:
Cited by:
Related to: