Procedural outcome and safety of percutaneous patent ductus arteriosus occlusion in adults
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Percutaneous device closure of patent ductus arteriosus (PDA) in infants and children is a frequently performed procedure. However, transcatheter closure is rare in adults, especially in developed countries, as most ducts are typically closed in childhood. PDA in adults poses unique challenges due to age-related comorbidities and some morphological changes in PDA that occur with advanced age. This study analyzes the safety and procedural success of adult PDA transcatheter closure. Materials and Methods: A retrospective single-center study analyzed 184 adult PDA device closures between July 2015 and July 2024. The study examined patient demographics, clinical aspects, procedural details, and immediate hospital outcomes. Outcome parameters focused on procedural success, complications, residual shunt, and improvement in symptoms. Results: = 20, 10.9%). The mean PDA diameter at its narrowest end was 6.17 ± 4.56 mm (1.2-17 mm). In total, 6.55% of patients exhibited duct calcification, and 2.73% presented with a PDA aneurysm. Severe pulmonary hypertension was present in 24 patients. Transcatheter intervention achieved a 100% success rate at 24 h postprocedure, with no residual flows at the 6-month follow-up. There was no mortality, device embolization, or aortic/pulmonary artery stenosis. Conclusions: Percutaneous device closure is a safe and successful treatment option for PDA in adults.
Source: Annals of Pediatric Cardiology
Institution: Rawalpindi Medical University
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7118256022