Work

Abdominal Imaging at Initial Diagnosis and Following Relapse in Children With Acute Lymphoblastic Leukaemia

Year: 2026

Type: article

Abstract: Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. It is characterised by the proliferation of immature lymphoid cells capable of infiltrating bone marrow, blood and extramedullary sites. Five-year overall survival rates exceed 90% with current multidrug chemotherapeutic regimens. This manuscript reviews the abdominal imaging features of leukaemic infiltration in children with ALL at the time of initial diagnosis and following relapse.

Source: Journal of Medical Imaging and Radiation Oncology

DOI: 10.1111/1754-9485.70065

Authors: Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck

Institutions: Princess Margaret Hospital for Children, Perth Children's Hospital, The Kids Research Institute Australia, The University of Western Australia, Curtin University

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze