Work

Analysis of Risk Prediction Model for Recurrence of Trigeminal Neuralgia After Percutaneous Balloon Compression

Year: 2026

Type: article

Abstract: Objective: Trigeminal neuralgia (TN) is a debilitating disorder characterized by severe facial pain. While percutaneous balloon compression (PBC) is an effective surgical treatment for TN, recurrence remains a significant concern, with varying reported rates. The identification of factors that contribute to recurrence after PBC is critical for improving treatment outcomes. However, existing predictive models for recurrence have limitations in accuracy and generalizability. This study aims to explore the influencing factors of TN recurrence after PBC and to construct a TN recurrence risk prediction model. Methods: = 131) in a ratio of 7:3. Patients were divided into two groups based on whether they experienced recurrence or not. Risk prediction models were constructed using three machine learning methods: logistic regression, random forest, and XGBoost. The area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, and specificity were used to evaluate the model performance. Results: Multivariate analysis showed that the duration of disease, pain type, balloon shape, compression time, and delayed disappearance of pain were influencing factors for TN recurrence after PBC, while facial numbness was a protective factor. All three predictive models exhibit high accuracy. In the modeling group, the AUC values for the logistic regression, random forest, and XGBoost models are 0.810, 0.824, and 0.816, respectively. Furthermore, the random forest model outperforms the other two models in terms of accuracy, sensitivity, and specificity. Additionally, external validation also demonstrates that the random forest model has good predictive value for TN after PBC (AUC = 0.835). Conclusion: The random forest model showed excellent performance in predicting TN recurrence after PBC, providing a powerful reference for clinical prevention.

Source: Pain Research and Management

DOI: 10.1155/prm/6688829

Authors: Ying Guo, Jing Feng, Yige Ma, Na Zhang, Jianheng Gu, Zhaoting Pei

Institutions: Harbin Medical University, Fourth Affiliated Hospital of Harbin Medical University

Language: English

Topic: Trigeminal Neuralgia and Treatments

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,830