Work

A case of necrotizing pneumonia leading to respiratory failure and tracheostomy

Year: 2026

Type: article

Abstract: Necrotizing pneumonia is a severe lung infection characterized by pulmonary necrosis and high mortality rates of up to 50%. It is typically caused by toxin-producing pathogens, such as Staphylococcus aureus and Klebsiella pneumoniae . Limited guidelines exist for its management, making its treatment challenging. Case report: We discuss a case of a 58-year-old Malay woman with no significant comorbidity but developed necrotizing pneumonia. The diagnosis was confirmed using computed tomography (CT) of the thorax. Treatment with carbapenem, oxazolidinone and corticosteroid led to significant recovery. Conclusion: To date, no specific anti-inflammatory treatments exist for severe necrotizing pneumonia. Since systemic inflammation and multi-organ failure drive mortality, management focuses on supportive care aimed at maintaining oxygenation and hemodynamic stability to improve outcomes in critically ill patients.

Source: IDCases

DOI: 10.1016/j.idcr.2025.e02480

Authors: Nurul 'Aifaa Mohd Azmi, Shao Keong Koeh, Tuan Sharifah Syuwaibah Tuan Zainal, Mohd Zulfakar Mazlan

Institutions: Universiti Sains Malaysia, Hospital Universiti Sains Malaysia

Language: English

Topic: Pneumonia and Respiratory Infections

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,370