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Primary Cardiac Lymphoma With Exceptional Long-Term Survival

Year: 2026

Type: article

Abstract: Primary cardiac lymphoma (PCL) is an uncommon extranodal lymphoma confined to the heart or pericardium at diagnosis and can mimic other cardiac disorders because of its nonspecific presentation. We report a 53-year-old man diagnosed in 2015 with diffuse large B-cell lymphoma involving the right atrium. He underwent surgical excision followed by six cycles of R-CHOP chemoimmunotherapy. Serial PET/CT and echocardiography confirmed sustained complete metabolic remission, and he remains disease-free 128 months after treatment. This case highlights the potential for prolonged survival in PCL when timely diagnosis, accurate histopathological confirmation, and appropriate therapy are provided.

Source: Cureus

DOI: 10.7759/cureus.100878

Authors: Sohini Ganesuni, Balasubramoniam K R, Rajesh Kannan R, Indu R Nair, Keechilat Pavithran

Institutions: Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham, Yashoda Hospital

Language: English

Topic: Cardiac tumors and thrombi

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7118663304