Silent Propagation of Classical Scrapie Prions in Homozygous K 222 Transgenic Mice

Year: 2025

Type: article

Abstract: environment. Our findings caution against including that polymorphism in breeding programs, because it could lead to emergence of asymptomatic silent prion carriers of classical scrapie among goat populations.

Source: Emerging infectious diseases

DOI: 10.3201/eid3112.250302

Authors: Natalia Fernández-Borges, Alba Marín-Moreno, Juan Carlos Espinosa, Sara Canoyra, Olivier Andréoletti, Juan María Torres

Language: English

Topic: Prion Diseases and Protein Misfolding

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Ministerio de Ciencia, Innovación y Universidades, European Commission, European Regional Development Fund, Agencia Estatal de Investigación

OpenAlex ID: W7119020343