Work

High-throughput C–H activation in a bead-beater homogenizer: fast and regioselective access to 2-arylindoles

Year: 2026

Type: article

Abstract: This work demonstrates the utility of a bead-beater homogenizer for high-throughput mechanosynthesis (HTMS), exemplified by Pd( ii )-catalyzed C2-H arylation of indoles in simple polypropylene vials with SS balls, affording products in just 9 min.

Source: RSC Mechanochemistry

DOI: 10.1039/d5mr00124b

Authors: Mainak Banerjee, Shravya B., Aboy Chatterjee, Shamima Hussain, Amtita Chatterjee

Institutions: Birla Institute of Technology and Science, Pilani - Goa Campus, Birla Institute of Technology and Science, Pilani

Language: English

Topic: Catalytic C–H Functionalization Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Birla Institute of Technology and Science, Pilani, UGC-DAE Consortium for Scientific Research, University Grants Commission

Award: G1986719887