A Nomogram Predicting Decreased Quality of Life in Patients with Keloids
Year: 2026
Type: article
Study design: Observational Study
Abstract: Shu Xu,1,* Yuting Huang,1,* Li Zhang,1,* Yuqi Wu,1 Hao Zhang,1 Jiawen Wu,1 Zhifeng Gu,2 Chen Dong2 1Department of Dermatology, HAffiliated Hospital of Nantong University, Nantong University, Nantong, People’s Republic of China; 2Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhifeng Gu, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226000, People’s Republic of China, Email [email protected] Chen Dong, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226000, People’s Republic of China, Email [email protected]: Most keloid patients have a low quality of life (QoL), which affects their prognosis. Our aim was to identify risk factors for a decreased QoL in patients with keloids and to create a predictive nomogram for this condition.Patients and Methods: The Dermatology Life Quality Index (DLQI) is used to assess patients’ QoL, with a DLQI score > 10 indicated a decreased QoL. We used multivariate logistic regression to assess QoL in patients with keloids for predictive modeling. We assessed the predictive and clinical value of the nomograms using the consistency index (C-index), area under the curve (AUC), and decision curve analysis (DCA).Results: The risk factors that associated with a decreased QoL in patients with keloids are smoking (OR = 2.463, 95% CI = 1.031– 5.880, P = 0.042), pain with pruritus (OR = 2.647, 95% CI = 1.232– 5.684, P = 0.013), and anxiety (OR = 5.294, 95% CI = 2.158– 12.987, P
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7119249855
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